BET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc-induced lymphoma cells.

Somsundar Veppil Muralidharan,Joydeep Bhadury,Lisa M. Nilsson,Lydia Green,Kevin G. McLure,Jonas A. Nilsson

BET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc-induced lymphoma cells.

2016

Somsundar Veppil Muralidharan
Joydeep Bhadury
Lisa M. Nilsson
Lydia Green
Kevin G. McLure
Jonas A. Nilsson

BET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc-induced lymphoma cells

Keywords:

Cell cycle
Unfolded protein response
Cancer research
Bromodomain
Apoptosis
DNA damage
Secretory pathway
Senescence
Growth factor receptor
Biology

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