Utilization of Sonography Compared With Magnetic Resonance Imaging in Determining the Cross-Sectional Area of the Median Nerve in a Sample of Working Macaca fascicularis A Preclinical Study

A preclinical study of 15 Macaca fascicularis monkeys was conducted to determine (1) the ability of detecting median mononeuropathy (MMN) within the median nerve after a work intervention and (2) the relationship between the layers of the median nerve during an acute inflammatory process by using sonography in conjunction with magnetic resonance imaging (MRI). Cross-sectional areas (CSAs) were imaged using MRI and sonography proximal to the carpal tunnel inlet (defined by the most distal portion of the radius) and further distal into the carpal tunnel (defined by the most proximal portion of the pisiform) at the prework exposure stage. CSAs measured on the outer edge of the median nerve were obtained from both modalities, at both anatomical locations. An intermodality t test demonstrated no statistical differences between the two sets of measurements (radius, P ≤ .15; pisiform, P ≤ .46). At the postwork exposure stage, sonographic measurements were obtained on the outer and inner borders of the median ner...