Simulation of the Rat Tibial Bone Density Changes with the Finite Element Method.

Objective To calculate changes of rat tibial density induced by mechanical load with the finite element method. Method A three-dimensional computer model was formed by processing the industrial CT image of rat tibia; bone remodeling results were predicted by using the internal bone remodeling theory presented by Beaupre in conjunction with the finite element method. Result The increments of the elements density and its distribution plot were obtained. Conclusion The simulation results agree well with the results of the biological experiment, so the simulation results were proved to be accurate.