Enantioselective synthesis of flavonoids. Part 51. Poly-oxygenated β-hydroxydihydrochalcones

Abstract Epoxidation of a series of poly-oxygenated chalcones with urea-hydrogen peroxide complex in THF in the presence of DBU and poly-( l )- or -( d )-leucine, followed by TBTH/AIBN catalysed ringopening, afforded β-hydroxydihydrochalcones in moderate to high enantiomeric excess and yield.