1,2,3,4-Tetrahydropyrimidinyl-1, 2,4-oxadiazole derivatives as muscarinic receptor agonist, and method for preparing the same

The present invention contains a novel 1,2,3,4-tetrahydro-pyrimidinyl, 1,2,4-oxadiazole derivatives and their preparation methods, and the novel compound which acts as a functional muscarinic receptor substance as an active ingredient It relates to a pharmaceutical composition. 1,2,3,4-tetrahydro-pyrido according to the present invention, pyrimidinyl-1,2,4-oxadiazole derivative is stored hypertension and senile dementia therapeutic agent exhibits a functional activity as muscarinic receptor material (muscarinic receptor agonist) , can be applied to a therapeutic agent associated with the brain disorders and central nervous system, it indicates a fringing choline and Millar comparable efficacy and Melinda drugs used for dementia treatment acts as an equivalent electronic (bioisoster) of the tetrahydropyridine as already clinical . Senile dementia, muscarinic receptor agonists, 1,2,3,4-tetrahydro-pyrimidinyl, 2,4-oxadiazole derivative