ClinicaI Curative Effect Observation of Integration of TraditionaI Chinese and Western Medicine on Eradication of HP infection

Objective:To obverse the curative effect of integration of traditional Chinese and western medicine(TCWM) on eradication of HP infection.Methods:85 patients with chronic gastritis or peptic ulcer or reflux esophagitis diagnosed by gastroscopy without using antibiotics and antisecretory drugs during 1 month with the positive HP by the rapid urease test and the histology were chosen and randomly divided into the TCWM group(42 cases) and the triple western medicine(TWM) group(43 cases).The TCWM group was treated bv one dose of Mieyou powder per day and Omeprazole 20 mg twice a day for 4 weeks.The TWM group was treated by Clarithromycine 0.25.Metronidazole 0.4 and Omeprazole 20 mg twice a day for 1 week.The clinical symptoms were observed after therapy.The case of negative 14C-UBT 4 weeks after therapy was regarded as eradication.9 cases stopped treatment for side effect were regarded as no effect.Results:The ratios of symptom disappeared in the TCWM group and the TWM group were 80.9% and 83.7% respectively.The ratios of eradication of the TCWM group and the TWM group were 66.6% and 72.0% respectively.There were no significant difference(P0.05).The ratios of stopped therapy for side effect of two groups were 4.76% and 16.2% respectively(P0.05).Conclusion:Integration of traditional Chinese and western medicine has good effect on eradication of HP infection.which is especially suitable for those with antibiotic resistance or severe adverse side effects.