Different Risk Factors for Graft Survival Between Living-Related and Deceased Donor Kidney Transplantation

Abstract The aim of this study was to determine distinctive risk factors for graft survival of living-related and deceased donor kidney transplantation (KTx). Methods Consecutive 536 living-related and 524 deceased donor kidney transplant recipients from February 2014 to December 2015 in a single center were enrolled for retrospective analysis. Graft survival was assessed with the Kaplan-Meier method, and the Cox proportional hazard model was used to determine independent risk factors of allograft survival. Results One-, 3-, and 5-year graft survival rates were 98.8%, 98.5%, and 97.2%, respectively, in living-related donor KTx and were 94.9%, 91.3%, and 91.3%, respectively, in deceased donor KTx (log-rank, P P  = .046), delayed graft function (HR, 5.785; P  = .02), and acute rejection (HR, 2.706; P  = .04); risks factors in deceased donor KTx were recipient age (HR, 1.066 per year; P  = .004), recipient history of diabetes mellitus (HR, 3.011; P  = .03), pretransplant positive panel reactive antibody (HR, 3.353; P  = .02), and donor history of hypertension (HR, 2.660; P  = .046). Conclusion Distinctive risk factors for graft survival of living-related and deceased donor KTx were found.