treated prevalent cases Heterogeneity of outcomes in schizophrenia: 3-year follow-up of

Background Careforpeoplewithschizophreniashouldaddressawiderangeofoutcomes, includingprofessionalandofoutcomes,includingprofessionalandconsumerperspectives.Aims Tomeasurechangesinpsycho-pathology,functioning,needsforcareandqualityoflife; to developpredictivemodelsforeachoutcomedomain;andtomodelsforeachoutcomedomain; andtoassessthefrequencyof ‘good’and‘poor’outcomes,asdefinedinaseriesofdifferentdefinitionsthatusecombinationsofthefourdomainsmeasured.MMetethodhod Three-year follow-upofaThree-yearfollow-upofa1-year-treatedprevalencecohortof107patientswithanICD^10diagnosisofschizophrenia attendingthe SouthVeronacommunity-basedmentalhealthservice.RReesusulltsts Meansymptomseverityandsometypesofneedsforcareworsen,butqualityoflifeshowsnochange.Functioningshowsanon-significanttrendtodeteriorate.Between32%and42%ofthevarianceinthefourkeyoutcomeswasexplainedbyourmodel.Differentdefinitionsof ‘good’and‘poor’outcomeincluded0^31%ofpatients, dependingonincluded 0^31%ofpatients,dependingonthedefinitionused.Conclusions The3-yearoutcomeforschizophreniadependsonthedomainofoutcomeused,whetherstafforpatientratingsareusedandthestringencyofthedefinitionsusedforgoodandpooroutcome.Declarationof interest NNoonene..TThehestudyhasbeensupportedbyagrantfromFondazioneMarioLugli(Roma).Fondazione MarioLugli(Roma).