Validation of Non-rigid Registration of Contrast-Enhanced MR Mammography Using Finite Element Methods

This paper presents a validation study for non-rigid registration of 3D contrast enhanced magnetic resonance mammography images. We compare the performance of two non-rigid registration algorithms based on single- and multilevel free-form deformations using B-splines and normalized mutual information. To assess the registration performance, we employ a biomechanical deformation simulator of patient motion likely to occur in vivo.