RESEARCH ARTICLE ANTIOXIDANT ACTIVITY OF BIOSYNTHESIZED PSIDIUM GUAJAVA LEAF EXTRACT MEDIATED SILVER NANOPARTICLES

Article History: Xxxxxxxxxxxxxxxxxxxxx Xxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx This report shows a rapid and eco -friendly method for green synthesis of silver nanoparticles from aqueous solution of silver nitrate using Psidium Guajavaleaf extract as reductant and stabilizer. These biosynthesized nanoparticles were characterized with the help of UV-Vis spectroscopy, Fourier transform infrared spectroscopy, X -ray diffraction (XRD). The UV-Vis spectra gave surface Plasmon resonance for s ynthesized silver nanoparticles at 430 nm. The XRD analysis showed that the AgNPs with grain size 30 nm are crystalline in nature and have face -centered cubic geometry. The FTIR measurement was carried out to identify the possible biomolecules responsible for efficient stabilization of silver nanoparticles. Free radicals are produced in normal and/or pathological cell metabolism. Oxidation is essential to many living organisms for the production of energy to fuel biological processes. However, the uncontrol led production of oxygen derived free radicals is involved in the onset of many diseases such as cancer, rheumatoid arthritis, cirrhosis and arteriosclerosis as well as in degenerative processes associated with aging. Hence, the present study deals with an tioxidant activity for biosynthesis of AgNPs using Psidium guajava leaf extract. Free radical scavenging potential of Psidium guajava synthesized silver nanoparticles was evaluated in vitro by using four different assays viz., DPPH radical scavenging assay and ABTs radical scavenging assay are also adopted. The results suggest that the silver nanoparticles from Psidium guajava can be potent natural antioxidants and can be essential for health preservation against oxidative stress related degenerative diseases, such as cancer.