Activation of AMP-Activated Protein Kinase Inhibits Albumin-Induced Endoplasmic Reticulum Stress and Apoptosis through Inhibition of Reactive Oxygen Species

Eun-Kyoung Lee,Jin Uk Jeong,Jai-Won Chang,Won Seok Yang,Soon Bae Kim,Su-Kil Park,Jung Sik Park,Sang-Koo Lee

Activation of AMP-Activated Protein Kinase Inhibits Albumin-Induced Endoplasmic Reticulum Stress and Apoptosis through Inhibition of Reactive Oxygen Species

2012

Eun-Kyoung Lee
Jin Uk Jeong
Jai-Won Chang
Won Seok Yang
Soon Bae Kim
Su-Kil Park
Jung Sik Park
Sang-Koo Lee

Background: Endoplasmic reticulum (ER) stress induced by urinary albumin plays an important role in tubulointerstitial injury. We have shown that albumin-induced

Keywords:

Internal medicine
ASK1
AMP-activated protein kinase
Metformin
Endocrinology
Apoptosis
Albumin
Biology
Biochemistry
Endoplasmic reticulum
Reactive oxygen species
Diabetes mellitus

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