Intra-Orbital Follicular Lymphoma and Intra-Oral MALT-Type Lymphoma in a Single Patient

An 81-year-old woman with intra-orbital follicular large-cell lymphoma and intra-oral low-grade B-cell lymphoma, compatible with MALT-type lymphoma, is reported. Several hematopathologic features indicated that the two morphologically different lymphomas were originated from a single clone of cells, but no definite evidence to confirm this possibility could be obtained. Result of chemotherapy indicated difference in sensi tivity of lymphoma cells of the two lesions to cytotoxic drugs.