Abstract 10372: A Clinical Drug-Drug Interaction Study of Imb-1018972, a Novel Investigational Cardiac Mitotrope in Phase 2 Development for the Treatment of Myocardial Ischemia and Hypertrophic Cardiomyopathy

Larry Tremaine,Suliman Al-Fayoumi,Jeroen van de Wetering,Thjis van Iersel,Jaikrishna Patel,Paul Chamberlin

Abstract 10372: A Clinical Drug-Drug Interaction Study of Imb-1018972, a Novel Investigational Cardiac Mitotrope in Phase 2 Development for the Treatment of Myocardial Ischemia and Hypertrophic Cardiomyopathy

2021

Larry Tremaine
Suliman Al-Fayoumi
Jeroen van de Wetering
Thjis van Iersel
Jaikrishna Patel
Paul Chamberlin

Background: IMB-1018972 (IMB-101) is a novel mitotropic agent designed to increase myocardial metabolic efficiency by shifting substrate utilization towards glucose through reducing fatty acid oxid...

Keywords:

myocardial ischemia
Pharmacology
metabolic efficiency
cardiac metabolism
Drug-drug interaction
Fatty acid
Medicine
Hypertrophic cardiomyopathy

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