Combination of at least two ligands 5HT6.

A medicament comprising an active substance combination comprising at least one compound (A), wherein said compound (A) is N- [3- (2-dimethylamino-ethyl) -1H-indol-5-yl] - 6-chloroimidazo [2,1-b] thiazole 5-sulfonamide 5 and at least one compound (B), wherein at least one compound (B) is SB-271046, and wherein the medicament optionally also comprises at least a pharmaceutical adjuvant.