Heterocyclizations in the pyrido[2,3-b]pyrazine series
1994
In this paper, we report the results of heterocyclizations in the pyrido[2,3-b]pyrazine series to give the pyrido[2,3-e] or [3,2-e]pyrrolo[1,2-a]pyrazine. The Clauson-Kaas reaction on 2,3-diaminopyridine is investigated; regioselectivity on the 3-amino group is shown by 1 H- and 13 C-nmr. Synthesis and reactivity of the original pyrazino[2,3-g]indolizine series is also reported
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