Dynamics of the binding and change of photosensitizers of phthalocyanine row concentration in malignant tumors: experimental results

The results of investigations of photosensitizers distribution, accumulation and outputting in the process of photodynamic therapy on the model of Erlikh carcinoma in the experiment are adduced. Phthalocyanines of Al, differing in technology of synthesis and content of sulfa groups, have been used. The character of photosensitizer binding has been determined by the change of its spectral characteristics after binding with albumin in vitro and by analysis of fine structure of fluorescence spectra in vivo.