Microbial metalloproteomes are largely uncharacterized

Metalloproteins are important in many biological processes, including respiration, photosynthesis and drug metabolism. Using genome sequences to predict the numbers and types of metal an organism uses is currently very challenging. These authors used a proteomics approach to identify and characterize a large number of a microorganism's metalloproteins on a genome-wide scale, and successfully separated and identified its cytoplasmic metalloproteins.