Quantitative Assessment of Air Trapping in Chronic Obstructive Pulmonary Disease Using Inspiratory and Expiratory Volumetric MDCT

OBJECTIVE. The purpose of our study was to determine the attenuation threshold value for the detection and quantification of air trapping using paired inspiratory and expiratory volumetric MDCT scans and to assess whether the densitometric parameter can be used for the quantification of airway dysfunction in chronic obstructive pulmonary disease (COPD) regardless of the degree of emphysema.MATERIALS AND METHODS. This study included 36 patients with COPD who underwent 64-MDCT. The entire lung volume with attenuation between –500 and –1,024 H was segmented as whole lung. The lung volume with attenuation between –500 and –950 H was segmented as limited lung, while the lung volume of less than –950 H was segmented as emphysema and eliminated. The relative volumes for limited lung (relative volumen–950) with attenuation values below thresholds (n) ranging from –850 to –950 H, and relative volume for whole lung (relative volume

Keywords:

• Respiratory disease
• Air trapping
• Radiology
• Pathology
• Densitometry
• Relative Volume
• Airway
• Lung
• Lung volumes
• Medicine
• COPD
• pulmonary disease

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