Orthogonal ligation: a three piece assembly of a PNA–peptide–PNA conjugate

Fabienne Burlina,David D. Dixson,Robert P. Doyle,Gérard Chassaing,Christopher N. Boddy,Philip E. Dawson,John Offer

Orthogonal ligation: a three piece assembly of a PNA–peptide–PNA conjugate

2008

Fabienne Burlina
David D. Dixson
Robert P. Doyle
Gérard Chassaing
Christopher N. Boddy
Philip E. Dawson
John Offer

A PNA–peptide–PNA conjugate was assembled from three fragments using a combination of native chemical ligation and an orthogonal, auxiliary-mediated ligation.

Keywords:

Combinatorial chemistry
Conjugate
Ligation
Native chemical ligation
Organic chemistry
Chemistry
Peptide

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