Visible‐Light‐Triggered Release of Nitric Oxide from N‐Pyramidal Nitrosamines
2012
Although many organic/inorganic compounds that release nitric oxide (NO) upon photoirradiation (phototriggered caged-NOs) have been reported, their photoabsorption wavelengths mostly lie in the UV region, because XNO bonds (X=heteroatom and metal) generally have rather strong π-bond character. Thus, it is intrinsically difficult to generate organic compounds that release NO under visible light irradiation. Herein, the structures and properties of N-pyramidal nitrosamine derivatives of 7-azabicyclo[2.2.1]heptanes that release NO under visible light irradiation are described. Bathochromic shifts of the absorptions of these nitrosamines, attributed to HOMO (n)–LUMO (π*) transitions associated with the nonplanar structure of the NNO moiety, enable the molecules to absorb visible light, which results in NNO bond cleavage. Thus, these compounds are innate organic caged-NOs that are uncaged by visible light.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
40
References
28
Citations
NaN
KQI