The synthesis of highly reactive, multi-functional α,β-epoxy- and α-acetoxy-nitrosamines

Abstract The synthesis of the reactive acetates, trans -3-acetoxy-2-hydroxy- N -nitrosomorpholine 3 and N -(1-acetoxy-2-hydroxyethyl)- N -nitrosoethanolamine 12, of two α-hydroxynitrosamines has been accomplished through the ring opening of the corresponding epoxides, NEMOR and 10 which were prepared by dimethyldioxirane oxidation of the vinyl nitrosamines.