STATIN–INDUCED DECREASE IN ABCA1 EXPRESSION VIA MIR33 INDUCTION MAY COUNTERACT CHOLESTEROL EFFLUX BY HIGH–DENSITY LIPOPROTEINS RAISED WITH THE CHOLESTERYL ESTER TRANSFER PROTEIN MODULATOR DALCETRAPIB

Eric Niesor,Gregory Schwartz,Gabriela Suchankova,Renée Benghozi,Markus Abt,David Kallend

STATIN–INDUCED DECREASE IN ABCA1 EXPRESSION VIA MIR33 INDUCTION MAY COUNTERACT CHOLESTEROL EFFLUX BY HIGH–DENSITY LIPOPROTEINS RAISED WITH THE CHOLESTERYL ESTER TRANSFER PROTEIN MODULATOR DALCETRAPIB

2013

Eric Niesor
Gregory Schwartz
Gabriela Suchankova
Renée Benghozi
Markus Abt
David Kallend

Reverse cholesterol transport is believed to be an important function of high–density lipoprotein (HDL). HDL–cholesterol from patients treated with the cholesteryl ester transfer protein (CETP) modulator dalcetrapib has been shown to increase cholesterol efflux in vitro in the absence of statin

Keywords:

Cholesterylester transfer protein
Statin
Efflux
Cholesterol
ABCA1
Medicine
Dalcetrapib
Reverse cholesterol transport
Pharmacology
Lipoprotein
Internal medicine
Cardiology

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