Oral Signs of Hematologic Disease

The oral manifestations of hematologic disorders are variable and sometimes resemble other local or systemic conditions. In addition to the cutaneous and systemic findings, the mucous membranes, periodontal tissues, salivary glands, and perioral tissues are often impacted. The clinical constellation may include nonspecific findings such as hemorrhage; fungal, viral, and bacterial infections; ulcerations; and edema. When discussing hematologic disorders, white blood cell, red blood cell, and platelet dyscrasias must be considered.