Dihydroquinazolinones via A3‐Type Reactions of N‐Carbamoyliminium Ions
2020
A variant of the A 3 coupling reaction was developed utilizing in situ generated N -carbamoyliminium ions. The tandem INCIC/A 3 -coupling sequence provided a facile one-pot synthesis of dihydroquinazolinone derivatives. The scope of the reaction was demonstrated in solution as well as on solid support. The reaction was further combined with peptide synthesis, SNAr reactions, CuAAC triazole formation or bromination, providing additional opportunities for further diversification of the dihydroquinazolinone scaffolds.
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
38
References
1
Citations
NaN
KQI