Compositional Changes in Muscle of Malignant Hyperthermia–Susceptible Pigs Due to Postmortem Alterations in Lipid Metabolism, Lipid Peroxidation and Protein Oxidation

Abstract Pigs with mutated calcium release channels are stress-susceptible and are known for increased postmortem metabolism which results in inferior meat quality. The lipid composition, lipid peroxidation, and oxidation of proteins of skeletal muscle homogenates from the longissimus muscle of pigs were investigated. Muscle tissue samples were obtained from malignant hyperthermia-resistant (MHR) and hyperthermia-susceptible (MHS) pigs in a postmortem time course. Differences in the n-3 polyunsaturated fatty acid composition with higher values in the susceptible pigs were detected (MHR versus MHS: 141±5 versus 116±4 μg/g wet wt.; P P P