Критерии отмены длительного приема системных кортикостероидов у больных бронхиальной астмой

The regression analysis of pulmonary function parameters was performed in 90 bronchial asthma patients being observed for 3 years and taking flunisolide and salmeterol. All the patients before the present study continually received systemic corticosteroids in the average daily dose of 11.2±0.5 mg for 6.8±0.7 years. The index of perspective abolishing of long-term taken systemic corticosteroids against the background of longterm therapy with flunisolide and salmeterol was calculated based on the regression analysis of forced expiratory volume for 1 s (FEV 1 ) and its growth in bronchodilating test (p=0.74, p<01). The abolishment of long-term taken systemic corticosteroids on the condition of continual treatment with inhaled steroids and long-acting β 2 -agonists is found to be possible in bronchial asthma patients having the index of <1.56.