Correlación entre el grosor de la grasa epicárdica y los marcadores bioquímicos de riesgo metabólico

2018 
espanolIntroduccion y objetivo La grasa epicardica se asocia a riesgo cardiovascular y aterosclerosis, y puede ser medida en forma fiable por ecocardiografia. Nuestro objetivo es evaluar si existe asociacion entre el grosor de la grasa epicardica (GGE) con marcadores bioquimicos de riesgo metabolico. Material y metodo Evaluamos 211 pacientes en quienes se realizo la medicion del GGE por ecocardiografia. Tambien se les se realizo glucemia, perfil de lipidos y niveles sericos de acido urico. Los metodos estadisticos usados fueros odds ratio y coeficiente de correlacion y determinacion de Pearson. Resultados No encontramos correlacion entre GGE con glucemia (r=0,064), colesterol total (r=0,005), colesterol ligado a lipoproteinas de alta densidad (r=–0,038), ni trigliceridos (r=0,118). Sin embargo, encontramos una correlacion significativa entre el GGE con la uricemia (r=0,415, p3mm en pacientes con hiperuricemia fue de 6,26 (IC 95%: 2,79-14, p Conclusion La hiperuricemia se correlaciona significativamente con el GGE en nuestra poblacion. La medicion del GGE por ecocardiografia puede ser un metodo de utilidad para evaluar el riesgo cardiovascular. EnglishIntroduction and objective Epicardial fat has been associated with increased cardiovascular risk and the development of atherosclerosis. Transthoracic echocardiography provides a reliable measurement of epicardial fat thickness (EFT). The aim of this study is to evaluate the relationship between EFT and biochemical parameters of metabolic risk. Material and method We assessed 211 patients who underwent echocardiography; EFT was measured by two cardiologists. In addition, patients’ glycaemia, lipid profile and serum uric acid were measured. Statistical analysis was performed with the Pearson coefficient test and Odds ratio. Results A positive correlation between EFT with glycaemia (r=.064), total serum cholesterol (r=.0056), high density lipoproteins (r=–.038), or with triglycerides (r=.118) was not observed. However, we did find a significant positive correlation between EFT and serum uric acid (r=.415, P3mm in patients with hyperuricemia was 6.26 (IC 95 2.79-14, P Conclusion Hyperuricemia is strongly associated with EFT in Mexican patients; EFT is a useful tool for global cardiovascular risk calculation.
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