EXPRESS: Reflective testing â a randomised controlled trial in primary care patients Running head: reflective testing.

BACKGROUNDReflective testing i.e. interpreting, commenting on and, if necessary, adding tests in order to aid the diagnostic process in a meaningful and efficient manner, is an extra service provided by laboratory medicine. However, there have been no prospective randomised controlled trials investigating the value of reflective testing in patient management.METHODSIn this trial, primary care patients were randomly allocated to an intervention group where general practitioners received laboratory tests results as requested as well as add-on test results with interpretative comments where considered appropriate by the laboratory specialist, or to a control group where general practitioners only received the laboratory test results requested. Patientsâ medical records were evaluated with a follow-up period of six months. For both groups, the primary outcome measures i.e. both intended action and actual management action, were blindly assessed by an independent expert panel as adequate, neutral or inadequate.RESULTSIn 226 of the 270 cases (84%) reflective testing was considered to be useful for the patient. In the intervention group (n=148), actual management by the general practitioner was scored as adequate (n=104; 70%), neutral (n=29; 20%) or not adequate (n=15; 10%). In the control group (n=122), these numbers were 57 (47%), 37 (30%) and 28 (23%). This difference was statistically significant (p<0.001).CONCLUSIONThis randomised controlled trial showed a positive effect of reflective testing in primary care patients on the adequacy of their management, as documented in medical records.