Abstract T MP37: Incidence of New or Worsening Renal Insufficiency (RI) Among Stroke Patients Receiving IV Contrast Dye: A Population-Based Study

Background: CT angiography (CTA) and conventional angiogram provide timely vascular anatomical information in stroke patients. However, the iodinated contrast dye may cause renal injury. Within a large, biracial population, we examined in-hospital incidence of new or worsening RI in stroke patients and its association with administration of intravenous (IV) dye. Methods: All residents of the Greater Cincinnati/Northern Kentucky region ≥ 20 years of age with ischemic stroke (IS), subarachnoidhemorrhage (SAH), or intracerebral hemorrhage (ICH) who presented to an emergency department in 2010 and survived at least two days were included. Medical records from the acute hospitalization were retrospectively reviewed, and age, race, sex, stroke risk factors, admission serum creatinine (Cr), vascular imaging, and metformin use were abstracted. Incidence of RI was assessed and stratified by use of IV dye. RI on presentation was defined as history of RI or ESRD or Cr ≥ 1.5 on admission. Development of RI during the...