Enantioselective Cu‐Catalyzed Functionalizations of Unactivated Alkenes

Copper hydride or copper boranyl species have already been used in reactions with Michael acceptors. Recently, notable advances have been described and the methodology extended to unactivated alkenes as well. In situ generated copper hydride ligated with chiral ligands is able to catalyze enantioselective aminations of alkenes. Furthermore, transient organocopper species formed upon initial hydrocupration of the alkene can be intercepted by other electrophiles such as imines, organohalides, or boranes.