Synthesis of some novel piperazine salts and their antimicrobial property against Escherichia coli and Bacillus subtilis

A series of substituted piperazine salts have been synthesized and tested for antimicrobial activity. The antimicrobial activity was tested against Escherichia coli and Bacillus subtilis. The study indicates that some of these derivatives showed significant activity against tested microbes. Based on the reported results, it may be concluded that an electronegative group is very vital in eliciting the desired biological effect.