Effects of Drospirenone 2 mg with 17- $\beta$ -Estradiol 1 mg on blood pressure and body weight in postmenopausal Korean women

Objective: To evaluate effects of Drospirenone 2 mg (DRSP) with 17--Estradiol 1 mg (E2) on blood pressure (BP) and body weight in postmenopausal Korean women. Methods: BP and body weight were measured at baseline and 3 months of the treatment. We compared the change in BP and body weight between normotensive (group 1, control) and high-normotensive (group 2) group during treatment. And we compared the change in BP and body weight between hypertensive group receiving anti-hypertensive with (group 3) and without (group 4, control) DRSP/E2 during treatment. Results: The mean systolic BP/diastolic BP of group 1 was not significantly decreased from baseline (116.9/75.0 mmHg) after treatment with DRSP/E2 for 3 months (116.1/73.2 mmHg) (P