Chromene derivatives substituted alkoxide as inhibitors of TCR-Nck interaction

2013 
Chromene derivatives substituted alkoxide as inhibitors of TCR-Nck interaction # The present invention relates to a group of compounds of formula (I) containing a chromene nucleus. #### IMAGE #### and having ability to inhibit lymphocyte proliferation by interaction of TCR with Nck, so the present invention also relates to the use of these compounds for treating diseases or conditions where such interaction triggers a complication as the reactions of transplant rejection, immune or autoimmune diseases, inflammatory diseases or proliferative diseases.
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