Highly conserved T-cell receptor junctional regions. Evidence for selection at the protein and the DNA level

We previously defined pigeon cytochrome c (pcc)-reactive T-cell clones in terms of antigen and MHC crossreactivity patterns. In this report, we isolated and sequenced the Tcr junctional regions of four additional clones in order to determine the degree of junctional diversity among clones which express identical V and J regions