Norlignans with Hyaluronidase Inhibitory Activity from Anemarrhena asphodeloides

Assay-guided fractionation of an MeOH extract of Anemarrhena asphodeloides Bunge has furnished two hyaluronidase inhibitory norlignans, cis-hinokiresinol (1) and 1,3-di-p-hydroxyphenyl-4-penten-1-one (2), and an inactive norlignan 4′-methyl-cis-hinokiresinol (3). Compound 2 is a new compound.