Growth characteristics of colonies in monolayer cultures of guinea pig spleen

In two independent series of experiments, in each of which 16 monolayer cultures of guinea pig spleen cells were set up (four at each time), the distribution of the colonies formed by their diameter was studied 6, 7, 10, and 12 days after explanation. At all times studied the distribution of the colonies corresponded to the normal law of distribution; this points to homogeneity of the colony-forming cell population in the hematopoietic organs of guinea pigs as regards their ability to form colonies in monolayer cultures.