Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes

Symen Ligthart,Rebecca V. Steenaard,Marjolein J. Peters,Joyce B. J. van Meurs,Eric J.G. Sijbrands,André G. Uitterlinden,Marc Jan Bonder,Albert Hofman,Oscar H. Franco,Abbas Dehghan

Tobacco smoking is associated with DNA methylation of diabetes susceptibility genes

2016

Symen Ligthart
Rebecca V. Steenaard
Marjolein J. Peters
Joyce B. J. van Meurs
Eric J.G. Sijbrands
André G. Uitterlinden
Marc Jan Bonder
Albert Hofman
Oscar H. Franco
Abbas Dehghan

Aims/hypothesis Tobacco smoking, a risk factor for diabetes, is an established modifier of DNA methylation. We hypothesised that tobacco smoking modifies DNA methylation of genes previously identified for diabetes.

Keywords:

Gene expression
Type 2 diabetes
DNA methylation
Locus (genetics)
Genetics
Risk factor
Genome-wide association study
Gene
Disease
Biology
Diabetes mellitus
CpG site
Medicine

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