Highly Enantioselective Control of Dynamic Cascade Transformations by Dual Catalysis : Asymmetric Synthesis of Polysubstituted Spirocyclic Oxindoles

The highly enantioselective (up to >99.5:0.5 er) synthesis of polysubstituted spirocyclic oxindoles with four new contiguous stereocenters, including the spiro all-carbon quaternary center, is d ...