Multiple lymphomatous polyposis of the gastrointestinal tract

: We studied three patients in whom histology revealed multiple lymphomatous polyposis of the gastrointestinal tract. It is a distinctive type of primary gastrointestinal lymphoma characterized by polypoid accumulations of lymphoma tissue involving long segments of the gastrointestinal tract. This lymphoma consists of a diffuse proliferation of small round lymphocytes and small cleaved cells and tends to an extraintestinal dissemination. Clinical behavior of this entity is more aggressive than that of the same primary nodal lymphoma. We discuss the evolution of opinions of this entity.