Abstract TP102: Human Placental Mesenchymal Stem Cells Derived Exosome-Angiotensin Converting Enzyme-2 Dependent Protection in Ischemic Stroke Injury

Mansoureh Barzegar,Yuping Wang,Jungmi W. Yun,Oleg Y. Chernyshev,Roger E. Kelley,Jonathan S. Alexander

Abstract TP102: Human Placental Mesenchymal Stem Cells Derived Exosome-Angiotensin Converting Enzyme-2 Dependent Protection in Ischemic Stroke Injury

2020

Mansoureh Barzegar
Yuping Wang
Jungmi W. Yun
Oleg Y. Chernyshev
Roger E. Kelley
Jonathan S. Alexander

Following thrombolytic therapy for stroke, ischemia/reperfusion (I/R) mediated inflammation often disrupts the blood brain barrier (BBB). This can enhance expression of endothelial adhesion markers...

Keywords:

Physical therapy
Mesenchymal stem cell
Stroke
Pharmacology
Angiotensin-converting enzyme 2
Blood–brain barrier
Inflammation
Medicine
Exosome
Ischemia
Stem-cell therapy

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