Effect of Biochemical Parameters in Cetylmyristeolate Treatment Against Freunds Adjuvant Induced Arthritis Model

The current research was to evaluate the effect of Cetylmyristeolate (CMO) in Freund€s complete adjuvant induced arthritis in rats by analyzing its biochemical parameters. The experimental study was performed on Wister rats, Freund€s complete adjuvant was injected to induce arthritis in tibiotarsal joint (IA) , CMO-500mg; 1g and CMO 100mg + MSM 200mg + glucosamine 500mg /day for 21 days were given. Blood was collected by intraocular puncture on days 1,7,14 and 21and ESR (mm), serum CRP (mg/l) and Rheumatoid factor (IU/ml) were studied, the results showed that marked reduction of arthritic and inflammatory effect by CMO- 500mg/day and 1gm/day as well as the combination of 100mg/day + glucosamine 500mg and MSM 200mg /day.