The Identification of a Novel Phosphodiesterase 4 Inhibitor, 1-Ethyl-5- -N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyridin-4-amine (EPPA-1), with Improved Therapeutic Index using Pica Feeding in Rats as a Measure of Emetogenicity
2009
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