Implantable Cardioverter-Defibrillator Therapy to Reduce Sudden Cardiac Death in Adults with Congenital Heart Disease: A Registry Study.

INTRODUCTION The Adult Congenital Heart Disease (ACHD) population is rapidly expanding. However, a significant proportion of these patients suffer sudden cardiac death. Recommending implantable cardioverter-defibrillator (ICD) insertion requires balancing need for appropriate therapy in malignant arrhythmia against the consequences of inappropriate therapy and procedural complications. Here we present long-term follow up data for ICD insertion in patients with ACHD from a large level 1 congenital cardiac centre. METHODS AND RESULTS All patients with ACHD undergoing ICD insertion over an 18 year period were identified. Data were extracted for baseline characteristics including demographics, initial diagnosis, ventricular function, relevant medication and indication for ICD insertion. Details regarding device insertion were gathered along with follow up data including appropriate and inappropriate therapy and complications. A total of 136 ICDs were implanted during this period: 79 for primary and 57 for secondary prevention. The most common congenital cardiac conditions in both groups were tetralogy of Fallot and transposition of the great arteries. Twenty-two individuals in the primary prevention group received appropriate anti-tachycardia pacing (ATP), 14 underwent appropriate cardioversion, 17 received inappropriate ATP and 15 received inappropriate cardioversion. In the secondary prevention group, 18 individuals received appropriate ATP, 8 underwent appropriate cardioversion, 8 received inappropriate ATP and 7 were inappropriately cardioverted. Our data demonstrate low complication rates, particularly with leads without advisories. CONCLUSIONS ICD insertion in the ACHD population involves careful balance of the risks and benefits. Our data show a significant proportion of patients receiving appropriate therapy indicating that ICDs were inserted appropriately. This article is protected by copyright. All rights reserved.