Phase Ia clinical trial of adoptively transferring peripheral blood-derived cytotoxic T lymphocytes targeting individual neo-antigens to treat patients with advanced solid tumor.

Bo Li,Xiaoshi Zhang,Geng Liu,Si Qiu,Zhaoduan Liang,Mingming Liu,Yan Gao,Rui Hua Xu

Phase Ia clinical trial of adoptively transferring peripheral blood-derived cytotoxic T lymphocytes targeting individual neo-antigens to treat patients with advanced solid tumor.

2019

Bo Li
Xiaoshi Zhang
Geng Liu
Si Qiu
Zhaoduan Liang
Mingming Liu
Yan Gao
Rui Hua Xu

e14025Background: Adoptive transfer of tumor infiltrating lymphocytes (TILs) targeting neo-antigens mediates complete and durable regression of solid tumor. However, the limited availability of fre...

Keywords:

Cancer research
Advanced Solid Tumor
Clinical trial
Antigen
Cytotoxic T cell
Pathology
Peripheral
Medicine
neo antigens
solid tumor
peripheral blood
Tumor-infiltrating lymphocytes
Adoptive cell transfer

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