Zhibai Dihuang Pill Combined With Dabuyin Pill Treatment of Children With Central Precocious Puberty: Clinical Analysis of 56 Cases

Objective To discuss effectiveness by zhibai dihuang pill combined dabuyin pill to children with central precocious puberty (CPP). Methods From August 2011 to April 2013, a total of 56 cases of children with CPP were recruited. According to different strategies for treatment they were divided into treatment group (n=28; age 0.05). Results Follow-up 6 months after treatment, there were significance difference between two groups among efficiencies, effectivenesses, in efficiencies and total effective rates (78.5% vs. 57.1%, 14.3% vs 17.9%, 7.2% vs. 25.0%, 92.8% vs. 75.0%; χ2=3.546, 2.314, 2.597, 12.114; P<0.05). Conclusions Curative effect of zhibai dihuang pill combined dabuyin pill is good for treatment children with CPP in this study. But whether it is worthy of clinical application multi-center, large-sample randomized controlled trial will be needed to further confirm the safety and effectiveness, etc.. Key words: central precocious puberty; treatment; zhibai dihuang pill combined dabuyin pill; child