N‐Heterocyclic Carbene‐Catalyzed Umpolung Formal [3+3] Cycloaddition of Enals with Isatogens: Access to Fused Indolin‐3‐ones with a Tetrasubstituted Carbon Stereocenter
2015
A novel synthetic method to access fused indolin-3-ones with a tetrasubstituted carbon stereocenter has been developed via NHC-catalyzed umpolung formal [3+3] cycloaddtion of enals with isatogens. This methodology could be also applied for the quick construction of the 6-5-5 tricyclic pyrrolo[1,2-a]indole skeleton which is frequently found as a core structure of many indole alkaloids.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
73
References
30
Citations
NaN
KQI