Применение метаболической терапии у полиморбидных больных с воспалительными заболеваниями пародонта на фоне гипертонической болезни
2016
Сellular pathogenetic mechanisms in the of target organs destruction in the patients with arterial hypertension (AH) play an important role. AH is accompanied by a deep, metabolic and functional disorders in the tissues of the body, including tissues of tooth-jaw system. Apoptosis is an integral component of the pathological process. The study of the currently applied metabolic drugs effects on cells apoptosis opens up new opportunities in the treatment of different diseases. Drugs including L-carnitine are perspective for patients with AH associated with inflammatory parodont disease (IPD). High antioxidant activity of levocarnitinum is confirmed in the conducted research and nonspecific antiapoptotic action in the conditions of pathological activity of apoptosis is established, besides the levocarnitin,s normalizing microcirculation action is noted.
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