Stroop event-related potentials as a bioelectrical correlate of frontal lobe dysfunction in multiple sclerosis

Background Dysfunction of higher cognitive abilities occurs in 40–60 % of people with multiple sclerosis (MS), as detected with neuropsychological testing, with predominant involvement of executive functions and processing speed. Event-related potentials to the Stroop are a bioelectrical correlate of executive function. We tested whether event-related potentials to the executive Stroop test may reflect executive dysfunction in MS.