OC-049 Rectal Neuroendocrine Tumours: Management And Survival In 60 Patients

Introduction Rectal neuroendocrine tumours (rNETs) are increasing in incidence, with more found incidentally on routine colonoscopy. Our aim is to retrospectively analyse a cohort of rNETs to characterise diagnostic features and clinical behaviour. Methods Patients (pts) with confirmed diagnosis of rNET were identified from a database. Results 60 pts evaluated, median age 55 years (range 23–78). Most common presentation was rectal bleeding n = 29 (48%). 29/60 pts had tumour 2 cm, 2/60 size was unknown. Of patients with tumour size 2 cm are currently alive. Tumour size >2 cm have poorer outcome than the other 2 groups (p Conclusion Tumours >2 cm are associated with poor prognosis. Chromogranin A is mostly normal even in advanced disease. Prospective studies are needed to determine progression free survival data for systemic therapy. Disclosure of Interest None Declared.