Abstract 16474: Arrhythmic Events in Patients With Cardiac Channelopathies Submitted to Local Dental Anesthesia. A Randomized Pilot Study

Ion channels disorders, such as Brugada Syndrome (BS), long QT syndrome (LQTS) and catecholaminergic polymorphic ventricular tachycardia (CPVT) may account for at least one-third of the unexplained sudden cardiac deaths. Dental care in patients with cardiac channelopathies (CCh) is controversial and a challenge due to potential risk of life-threatening events. We assessed the hypothesis that the use of local dental anethesia with lidocaine with or without epinephrine can be safe, not resulting in life-threatening arrythymias (hemodinamically unstable arrhythmias or appropriate device shocks) in selected patients with CCh. Methods: Pilot randomized double-blind trial comparing the use of lidocaine 2% without vasoconstrictor and with 1:100,000 epinephrine in patients with CCh, under restorative dental treatment in two sessions, wash-out period of 7 days (cross-over trial). A 28h - Holter monitoring was performed in all patients. Specific records were also conducted in three time periods by 12-lead ECG, digi...